| Rheumatic conditions are typically characterized by pain,  aching, stiffness and swelling in and around one or more joints. The symptoms  can develop gradually or suddenly. Certain rheumatic conditions can also  involve the immune system and various internal organs of the body.
 Some forms of arthritis, such as rheumatoid arthritis and  lupus, can affect multiple organs and cause widespread symptoms.
 
 Arthritis is more common among adults aged 65 years or  older, but people of all ages (including children) can be affected.
 
 
  What causes arthritis? There is no single cause of all types of arthritis; the  cause or causes in any given case vary according to the type or form of  arthritis. Potential causes for arthritis may include:
 
 Potential causes for  arthritis may include:
 • Injury - leading to degenerative arthritis
 • Abnormal metabolism - leading to gout and pseudogout
 • Inheritance - such as in osteoarthritis
 • Infections - such as in the arthritis of Lyme disease
 • Immune system dysfunction - such as in RA and SLE.
 Most types of arthritis are caused by a combination of many  factors working together, although some arthritis conditions have no obvious  cause and appear to be unpredictable in their emergence.
 
 Some people may be more susceptible to certain arthritic  conditions due to their genetic makeup. Additional factors, such as previous  injury, infection, smoking and physically demanding occupations, can interact  with a person's genes to further increase the risk of arthritis.
   
 Signs and symptoms of  arthritis
 Just as the causes of different types of arthritis can vary  widely, the pattern and location of symptoms of arthritis can also vary  depending on the type.
 
 Arthritis symptoms can develop gradually or suddenly, and as  arthritis is most often a chronic disease, symptoms may come and go, or persist  over time.
 
 There are four key warning signs of arthritis that should  prompt a discussion with a health care provider. These include:
  1) Pain. Pain from arthritis can be constant, or it may come and go. Pain might be  isolated to one place or felt in many parts of the body
 
 2) Swelling. Some types of arthritis cause the skin over the  affected joint to become red and swollen, and to feel warm to the touch
 3) Stiffness. Stiffness is a typical arthritis symptom, with  some forms of arthritis causing increased stiffness upon waking up in the  morning, after sitting at a desk, or after sitting in a car for a long time,  and others resulting in stiffness after exercise or characterized by persistent  stiffness
 
 4) Difficulty moving a joint. Moving a joint or getting up from  a chair should not be hard or painful and can indicate arthritis or other joint  problem.
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