dupuytren's disease
Dr. Somesh Deb

What causes Dupuytren's Disease?

Dupuytren's Contracture Treatment

A Dupuytren's contraction is caused by an abnormal accumulation of collagen (scar) in the tissue beneath the skin of the palm of the hand. Xiaflex breaks down excessive collagen by disrupting its chemical structure.

Why is Dupuytren's contracture called Viking disease?

The Vikings and Baron Dupuytren's disease. Dupuytren's disease (DD) is an ancient affliction of unknown origin. It is defined by Dorland as shortening, thickening, and fibrosis of the palmar fascia producing a flexion deformity of a finger.

Can Dupuytren contracture be cured?

The goal of treatment for Dupuytren's is to reduce the symptoms and disability caused by the disease. At this time, however, there is no treatment to stop Dupuytren's contracture from getting worse.

Is Dupuytren's Contracture and autoimmune disease?

The immune system is involved, but not exactly like an autoimmune disease. Because it affects the connective tissues, it is a rheumatic disease, but because there is not yet an effective medicine, treated as a surgical disease. Treatment is for correction of deformity from Dupuytren contracture.